Table 2. Observed Means for Primary and Secondary Outcomes.
| Mean (SD) | ||||
|---|---|---|---|---|
| CXA-UP | WL | |||
| ITT (n = 120) | PP (n = 48) | ITT (n = 80) | PP (n = 61) | |
| Primary outcomes | ||||
| PCL-5 score | ||||
| Pretreatment | 51.4 (15.5) | 50.4 (17.1) | 50.7 (14.3) | 51.5 (13.6) |
| Posttreatment | 15.3 (13.8) | 15.3 (13.8) | 46.4 (14.5) | 46.4 (14.5) |
| 3-mo Follow-up | 10.8 (14.6) | 10.8 (14.6) | NA | NA |
| PHQ-depression score | ||||
| Pretreatment | 24.9 (6.6) | 24.3 (6.4) | 24.3 (5.7) | 24.6 (6.8) |
| Posttreatment | 13.1 (6.7) | 13.1 (6.7) | 24.7 (6.5) | 24.7 (6.5) |
| 3-mo Follow-up | 12.9 (5.3) | 12.9 (5.3) | NA | NA |
| PHQ-anxiety score | ||||
| Pretreatment | 16.8 (3.3) | 16.7 (3.5) | 17.1 (3.0) | 17.4 (2.9) |
| Posttreatment | 9.87 (3.6) | 9.87 (3.6) | 16.9 (3.2) | 16.9 (3.2) |
| 3-mo Follow-up | 10.0 (3.9) | 10.0 (3.9) | NA | NA |
| PHQ-somatic score | ||||
| Pretreatment | 22.7 (4.8) | 22 (5.1) | 21.9 (4.5) | 21.8 (4.5) |
| Posttreatment | 14.3 (5.5) | 14.3 (5.5) | 22.1 (4.8) | 22.1 (4.8) |
| 3-mo Follow-up | 15.2 (4.6) | 15.2 (4.6) | NA | NA |
| Secondary outcomes | ||||
| ODSIS score | ||||
| Pretreatment | 13.3 (4.6) | 12.5 (4.4) | 13.1 (4.9) | 12.9 (5.0) |
| Posttreatment | 1.8 (3.1) | 1.8 (3.1) | 11.8 (5.4) | 11.8 (5.4) |
| 3-mo Follow-up | 2.6 (4.3) | 2.6 (4.3) | NA | NA |
| OASIS score | ||||
| Pretreatment | 12.7 (5.0) | 12.7 (4.1) | 12.3 (5.0) | 12.1 (4.9) |
| Posttreatment | 1.7 (2.7) | 1.7 (2.7) | 10.7 (4.1) | 10.7 (4.1) |
| 3-mo Follow-up | 3.0 (4.3) | 3.0 (4.3) | NA | NA |
| Q-LES-Q score | ||||
| Pretreatment | 43.0 (8.1) | 43.6 (9.3) | 43.6 (8.0) | 43.5 (8.2) |
| Posttreatment | 54.8 (7.2) | 54.8 (7.2) | 44.3 (8.2) | 44.3 (8.2) |
| 3-mo Follow-up | 58.1 (8.5) | 58.1 (8.5) | NA | NA |
| WHODAS score | ||||
| Pretreatment | 1.3 (0.8) | 1.3 (0.7) | 1.2 (0.7) | 1.2 (0.7) |
| Posttreatment | 0.4 (0.4) | 0.4 (0.4) | 1.3 (0.7) | 1.3 (0.7) |
| 3-mo Follow-up | 1.0 (0.9) | 1.0 (0.9) | NA | NA |
Abbreviations: CXA-UP, contextual/cultural adaptation of the Unified Protocol; ITT, intent-to-treat; NA, not applicable; OASIS, Overall Anxiety Severity and Impairment Scale; ODSIS, Overall Depression Severity and Impairment Scale; PCL-5, posttraumatic stress disorder checklist for DSM-5; PHQ, Patient Health Questionnaire; PP, per protocol; Q-LES-Q, Quality-of-Life Enjoyment and Satisfaction Questionnaire; WHODAS, World Health Organization Disability Assessment Scale; WL, waitlist.