Table 5.
High Contrast Visual Acuity | Low Contrast Visual Acuity | |||||||||||||||
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Enrollment (N eyes = 32) | 6 Months (N eyes = 31) | 1 Year (N eyes = 32) | 2 Years (N eyes = 32) | Enrollment (N eyes = 32) | 6 Months (N eyes = 30) | 1 Year (N eyes = 31) | 2 Years (N eyes = 30) |
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N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | |||||||||
Visual acuity in affected eye(s), Snellen Equivalent (Number of Letters) | ||||||||||||||||
Worse than 20/800 (<5) | 7 | (22%) | 1 | (3%) | 1 | (3%) | 1 | (3%) | 18 | (56%) | 5 | (17%) | 5 | (16%) | 4 | (13%) |
20/250 to 20/800 (5–30) | 7 | (22%) | 1 | (3%) | 1 | (3%) | 1 | (3%) | 8 | (25%) | 2 | (7%) | 2 | (6%) | 1 | (3%) |
20/50 to 20/200 (35–65) | 6 | (19%) | 3 | (10%) | 3 | (9%) | 2 | (6%) | 4 | (13%) | 18 | (60%) | 14 | (45%) | 16 | (53%) |
20/20 to 20/40 (70–85) | 9 | (28%) | 15 | (48%) | 13 | (41%) | 16 | (50%) | 2 | (6%) | 5 | (17%) | 10 | (32%) | 9 | (30%) |
Better than 20/20 (>85) | 3 | (9%) | 11 | (35%) | 14 | (44%) | 12 | (38%) | 0 | (0%) | 0 | (0%) | 0 | (0%) | 0 | (0%) |
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Mean (95% CI) logMAR VA (95% CI)b | 0.81 (0.62 to 1.0) |
0.14 (−0.05 to 0.33) |
0.12 (−0.07 to 0.31) |
0.11 (−0.08 to 0.30) |
1.45 (1.25 to 1.64) |
0.78 (0.58 to 0.97) |
0.69 (0.50 to 0.89) |
0.68 (0.48 to 0.88) |
VA=visual acuity, SD=standard deviation, CI = confidence interval
logMAR converted to Snellen as follows: −0.2 = 20/12; −0.1 = 20/16; 0 = 20/20; 0.1 = 20/25; 0.2 = 20/32; 0.3 = 20/40; 0.4 = 20/50; 0.5 = 20/63; 0.6 = 20/80; 0.7 = 20/100; 0.8 = 20/125; 0.9 = 20/160; 1 = 20/200; 1.1 = 20/250; 1.2 = 20/320; 1.3 = 20/400; 1.4 = 20/500; 1.5 = 20/640; 1.6 = 20/800; 1.7 = <20/800
Adjusted for inter-eye correlation between eyes.