Table 2.
Correlation between ficolin-3 expression and clinicopathological characteristics
| Clinical parameter | All cases | FCN3 grade 1, 2 N (%) |
FCN3 grade 3, 4 N (%) |
p-value |
|---|---|---|---|---|
| No | 87 | 26 | 61 | |
| Sex | ||||
| Male | 68(78.2) | 21(80.8) | 47(77.1) | 0.784 |
| Female | 19(21.8) | 5(19.2) | 14(23.0) | |
| Age (yr) | ||||
| <65 | 11(12.6) | 15(57.7) | 40(65.6) | 0.485 |
| ≥65 | 76(87.4) | 11(42.3) | 21(34.4) | |
| Alcohol drinking | ||||
| Yes | 53(60.9) | 13(50.0) | 40(65.6) | 0.173 |
| No | 34(39.1) | 13(50.0) | 21(34.4) | |
| Tumor size (cm) | ||||
| <5 | 58(66.7) | 14(53.9) | 44(72.1) | 0.098 |
| ≥5 | 29(33.3) | 12(46.2) | 17(27.9) | |
| Etiology | ||||
| HCC | 17(19.5) | 5(19.2) | 12(19.7) | 0.962 |
| HCC/HBV | 43(49.4) | 14(53.9) | 29(47.5) | 0.590 |
| HCC/HCV | 24(27.6) | 7(26.9) | 17(27.9) | 0.928 |
| HCC/HBV/HCV | 3(3.5) | 0(0.0) | 3(4.9) | 0.250 |
| Pathological differentiation | ||||
| Well | 15(17.2) | 2(7.7) | 13(21.3) | 0.124 |
| Moderately | 65(74.7) | 20(76.9) | 45(73.8) | 0.757 |
| Poorly | 7(8.1) | 4(15.4) | 3(4.9) | 0.100 |
| TNM stage | ||||
| I | 50(57.5) | 12(46.2) | 38(62.3) | 0.236 |
| II | 21(24.1) | 8(30.8) | 13(21.3) | 0.414 |
| IIIa-IVb | 16(18.4) | 6(23.1) | 10(16.4) | 0.548 |
| Early recurrence | ||||
| Absent | 35(40.2) | 10(38.5) | 25(41.0) | 0.826 |
| Occurs | 52(59.8) | 16(61.5) | 36(59.0) | |
| Survival status | ||||
| Survival | 57(65.5) | 13(50.0) | 44(72.1) | 0.047 |
| Death | 30(34.5) | 13(50.0) | 17(27.9) |
FCN3, ficolin-3; HCC, hepatocellular carcinoma; HBV, hepatitis B virus; HCV, hepatitis C virus.