Table 4.
Multivariate analysis of factors affecting overall survival in the patients with hepatocellular carcinoma using a Cox proportional hazard model
| Variable | Hazard ratio | 95% CI | p-value |
|---|---|---|---|
| Age: ≥65 years versus <65 years | 2.702 | 1.128-6.819 | 0.025 |
| Sex: Male versus female | 0.895 | 0.304-3.038 | 0.848 |
| Differentiation status: | |||
| Poorly versus well and moderately | 3.923 | 1.262-11.191 | 0.020 |
| Hepatitis B Virus: Positive versus negative | 0.590 | 0.210-1.800 | 0.338 |
| Hepatitis C Virus: Positive versus negative | 0.992 | 0.371-2.926 | 0.987 |
| Tumor size: >5 cm versus ≤5 cm | 1.460 | 0.472-4.170 | 0.497 |
| Stage: 3, 4 versus 1, 2 | 1.810 | 0.604-5.546 | 0.287 |
| Ficolin-3 in tumor: High versus low | 0.623 | 0.262-1.613 | 0.315 |
In multivariate Cox regression analysis, values included for analysis were age, sex, differentiation status, hepatitis B Virus, hepatitis C Virus, tumor size, stage, and ficolin-3 in tumor.