Table 3.

Use of antiplatelet therapy in patients with MCI or dementia and CSVD.

	Recent small subcortical infarct	Lacune of presumed vascular origin with symptomatic atherosclerosis	Lacune of presumed vascular origin without symptomatic atherosclerosis	Lacune of presumed vascular origin with >5–10 CMBs and no symptomatic atherosclerosis	CSVD without lacunes, with symptomatic atherosclerosis	CSVD without lacunes, without symptomatic atherosclerosis
Indicated	SAPT & DAPT	SAPT			SAPT
Possibly indicated			SAPT			SAPT
Contraindicated		DAPT	DAPT	SAPT & DAPT	DAPT	DAPT

CMB denotes cerebral microbleeds; DAPT, dual antiplatelet therapy; and SAPT, single antiplatelet therapy.