Date | Event | Description |
---|---|---|
11 April 2013 | Amended | NIHR acknowledgement inserted |
11 February 2013 | New search has been performed | New literature search run and new trials incorporated. |
11 February 2013 | New citation required and conclusions have changed | Review updated following new search in February 2013. Five outstanding study reports (for DE‐SOLO; PASSION; SPAIN; STYLE; SYMPHONIE) have contributed new data to this review on 4560 adults comparing single inhaler therapy with current best practice. The additional data shows that single inhaler therapy also significantly reduced exacerbations requiring oral steroids in comparison to current best practice, although the absolute reduction was smaller in comparison to current best practice than in comparison to inhaled steroid maintenance. The title has been expanded to contain both comparator groups. We added 'Summary of findings' tables and incorporated the GRADE judgements within the review text. We rewrote a significant proportion of the review. |
11 November 2009 | Amended | Typological errors corrected (doses corrected to mcg not mg). The Sovani study was designed to assess compliance with inhaled (not oral) corticosteroids. |