Table 3.
Characteristic | Class 1 (n=5527) |
Class 2 (n=2411) |
Class 3 (n=327) |
P value |
Age (years) | 44.5±10.8 | 57.0±11.3 | 63.0±8.4 | <0.001 |
Women | 3046 (55.1%) | 1012 (42.0%) | 87 (26.6%) | <0.001 |
Caucasian ethnicity | 5239 (95.4%) | 2288 (96.1%) | 317 (97.8%) | 0.062 |
Follow-up duration (years) | 9.3±2.0 | 9.2±2.1 | 8.5±2.6 | <0.001 |
No of comorbidities | 1.0 (0.0–1.0) | 2.0 (2.0–3.0) | 4.0 (3.0–4.0) | <0.001 |
0 | 1424 (29.0%) | 0 (0.0%) | 0 (0.0%) | |
1–3 | 3863 (73.1%) | 2039 (91.5%) | 128 (42.5%) | |
≥4 | 0 (0.0%) | 190 (8.5%) | 173 (57.5%) | |
Hypertension | 0 (0.0%) | 2337 (98.3%) | 205 (64.9%) | <0.001 |
Heart failure | 0 (0.0%) | 0 (0.0%) | 18 (5.5%) | <0.001 |
Type 2 diabetes | 53 (1.0%) | 201 (8.5%) | 56 (17.6%) | <0.001 |
Hypercholesterolaemia | 69 (1.3%) | 103 (4.6%) | 189 (59.6%) | <0.001 |
Obesity | 531 (9.7%) | 694 (29.0%) | 62 (19.1%) | <0.001 |
Previous myocardial infarction | 5 (0.1%) | 0 (0.0%) | 246 (75.9%) | <0.001 |
Previous stroke | 28 (0.5%) | 36 (1.5%) | 17 (5.3%) | <0.001 |
Peripheral artery disease | 82 (1.5%) | 152 (6.7%) | 57 (18.8%) | <0.001 |
Renal impairment | 120 (2.2%) | 257 (10.7%) | 99 (27.5%) | <0.001 |
Microalbuminuria | 3597 (65.1%) | 1895 (78.6%) | 267 (81.7%) | <0.001 |
Latent class analysis based on hypertension, heart failure, type 2 diabetes, hypercholesterolaemia, obesity, previous myocardial infarction, previous stroke, peripheral artery disease, renal impairment, microalbuminuria and incident atrial fibrillation.