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. 2023 Apr 28;31(2):239–248. doi: 10.5606/tgkdc.dergisi.2023.23455

Table 3. Comparison of pre- and postoperative pain mediator indexes.

Variables Subxiphoid group (n=54) Control group (n=54) t-value p
Mean±SD Mean±SD
5-HT (ng/L)        
D1 (preoperative) 157.5±96.3 147.0±96.4 0.566 0.573
D1 214.5±107.7 272.1±116.0 -2.678 0.009
D7 184.8±100.9 228.4±73.4 -2.565 0.012
PGE2 (pg/mL)        
D1 (preoperative) 144.5±42.4 126.9±57.2 1.818 0.072
D1 230.4±36.7 277.8±63.1 -4.763 <0.001
D7 176.4±39.0 200.8±51.4 -2.782 0.006
ACTH (ng/mL)        
D1 (preoperative) 27.3±19.0 30.9±20.2 -0.967 0.336
D1 48.7±24.0 61.4±23.0 -2.808 0.006
D7 36.0±19.2 52.2±25.9 -3.698 <0.001
NPY (pg/L)        
D1 (preoperative) 127.0±33.0 116.9±33.4 1.578 0.118
D1 171.6±31.0 187.6±47.5 -2.075 0.040
D7 129.0±36.3 153.9±45.0 -3.163 0.002
SD: Standard deviation; 5-HT: 5-hydroxytryptamine; D1: First day after surgery; D7: Seventh day after surgery; PGE2: Prostaglandin E2; ACTH: Adrenocorticotropic hormone; NPY: Neuropeptide Y.