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. 2023 Apr 28;31(2):239–248. doi: 10.5606/tgkdc.dergisi.2023.23455

Table 4. Comparison of pre- and postoperative stress response indicators.

Variables Subxiphoid group (n=54) Control group (n=54) t-value p
Mean±SD Mean±SD
IL-1β (pg/mL)        
D1 (preoperative) 2.8±3.3 3.8±1.7 -1.924 0.057
D1 16.7±7.1 196±8.2 -1.995 0.049
D7 10.7±1.6 14.2±3.1 -7.385 <0.001
IL-6 (pg/mL)        
D1 (preoperative) 2.6±1.8 3.0±1.356 -1.231 0.221
D1 28.0±14.1 40.0±16.5 -4.076 <0.001
D7 8.6±4.5 12.6±3.9 -4.888 <0.001
TNF-α (ng/mL)        
D1 (preoperative) 8.2±5.6 7.3±3.3 1.045 0.298
D1 25.3±8.1 33.6±13.4 -3.888 <0.001
D7 10.2±4.7 18.2±9.0 -5.831 <0.001
C-reactive protein (mg/L)        
D1 (preoperative) 6.2±2.9 51±3.1 1.863 0.065
D1 44.7±44.2 69.6±75.6 -2.091 0.039
D7 11.4±10.0 27.1±18.6 -5.480 <0.001
SD: Standard deviation; IL-1β: Interleukin 1β; D1: First day after surgery; D7: Seventh day after surgery; IL-6: Interleukin 6; TNF-α: Tumor necrosis factor-alpha.