Table 1.
Baseline demographics and CT characteristics
| Characteristics | Low cardiac troponin (<5 ng/L) n=81* | Intermediate cardiac troponin (5 ng/L-99th centile) n=161* | P value † |
|---|---|---|---|
| Age | 57+11 | 64+12 | <0.001 |
| Male sex | 51 (63) | 116 (72) | 0.15 |
| Smoking history | 46 (57) | 86 (53) | 0.6 |
| Diabetes mellitus | 4 (4.9) | 28 (17) | 0.007 |
| Hypertension | 29 (36) | 75 (47) | 0.11 |
| Hyperlipidaemia | 20 (25) | 31 (19) | 0.6 |
| Family history of coronary artery disease | 27 (33) | 62 (39) | 0.4 |
| Previous myocardial infarction | 12 (15) | 36 (22) | 0.2 |
| GRACE score | 87+25 | 97+25 | 0.005 |
| Estimated glomerular filtration rate (mL/min/1.73 m2) | 89+14 | 82+18 | <0.001 |
| Any coronary artery disease | 35 (43) | 116 (72) | <0.001 |
| Obstructive coronary artery disease | 16 (20) | 51 (32) | 0.050 |
| Segment-involved score | 0 (0–3) | 2 (0–6) | <0.001 |
| Segment severity score | 0 (0–4) | 3 (0–9) | <0.001 |
| CT-Leaman score | 0 (0–5) | 5 (0–10) | <0.001 |
| Quantitative plaque analysis | |||
| Total plaque burden (%) | 0 (0–32) | 33 (0–47) | <0.001 |
| Non-calcified plaque burden (%) | 0 (0–28) | 26 (0–37) | <0.001 |
| Calcified plaque burden (%) | 0 (0–3.1) | 2.0 (0–7.5) | <0.001 |
| Low-attenuation plaque burden (%) | 0 (0–0.97) | 0.92 (0–3.16) | <0.001 |
*
Median (IQR), mean±SD or n (%).
†
Wilcoxon rank-sum test, Pearson’s χ2 test, Fisher’s exact test or Student’s t-test.
GRACE, Global Registry of Acute Coronary Events.