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. 2023 Jun 21;82(8):674–694. doi: 10.1093/jnen/nlad046

Figure 28.

Figure 28.

A typical new plaque filled with foamy macrophages. The halo effect is due in part to myelin loss and the presence of numerous gemistocytic astrocytes. Commencing clearing around the central vessel is due to beginning migration of foamy macrophages to the perivascular space of the vessel (Case 14, frozen section, Oil Red O, ×80).