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Chronic MS. An old, demyelinated plaque in the cerebellum (no lipid macrophages, no LFB-positive macrophages). Ramified microglia are present in demyelinated tissue, and are somewhat more numerous in bordering myelinated tissue where there are also microglial nodules. Monocytes were relatively common in the plaque and in bordering tissue (Case 17, CD45, ×80).
