Table 2.
Descriptive clinical and pathological features in an Italian cohort of adrenocortical carcinomas
| No. of cases | 201 |
| F/M | 118/83 |
| Mean age (range) | 47 (3–85) |
| Functional status | (known in 157 cases) |
| Not functioning | 76 |
| Cortisol | 52 |
| Cortisol + androgens | 10 |
| Androgens/estrogens | 6/2 |
| Aldosterone | 6 |
| “Hypertension” | 5 |
| Follow-up | (known in 188 cases) |
| NED/DOC | 69 |
| AWD | 47 |
| DOD | 72 |
| Location left/right adrenal | (known in 179 cases) 102/75a |
| Mean size, cm (range) | 11.3 (1.6–28) |
| Mean weight, g (range) | 480 (8–4,000) |
| Mean Weiss score | 6.25b |
| Weiss score 3–5/6–9 | 71/118b |
| Pediatric | 1 |
| Myxoid variant | 20 |
| Oncocytic variant | 22 |
| Sarcomatoid variant | 0 |
NED no evidence of disease, AWD alive with disease, DOC died of unrelated causes, DOD died of disease
aTwo bilateral tumors
bNot applicable in 12 cases because of metastases, biopsies, post-chemotherapy, or radiotherapy