Table 3.

Minimal requirements for pathological reporting

Macroscopy (one paraffin inclusion × cm, with special reference to the capsule/invasive front)

- Integrity of the sample, including tumor surface

- Size (three dimensions) and weight

- Description of the cut surface

- Description of the tumor borders, including presence and integrity of the tumor capsule, adhesion/invasion of adjacent tissues/structures

- Presence of residual adrenal tissue

Microscopy

- Type of scoring system applied (Weiss system to be preferred)

- Description of each individual parameter considered (mandatory to specify the numerical value of mitotic index in 50 high-power fields)

- Status of the resection margins

- Immunoprofile, if performed

- Ki-67 labeling indexa

Diagnosis

- Diagnosis, including variants

- pTNM stage (specify which, for example, AJCC/WHO or ENSAT) [13]

^aBased on recent literature data and according to the Hôpital Cochin experience, some more immunohistochemical markers may be added but are still not recommended in the daily practice, and include p53, cyclin E, and beta-catenin