Table 1.
Clinical manifestation of patients with craniopharyngioma at the diagnosis
| Patients | Sex | Age at the diagnosis (years) | Endocrine involvement | Hypothalamic dysfunctions | Neurological manifestations | Visual disturbances |
|---|---|---|---|---|---|---|
| 1 | M | 6 | Hyperprolactinemia | Somnolence | Headache | Diplopia |
| 2 | M | 6 | GHD | OB | Headache, nausea/vomit | Visual deterioration |
| 3 | F | 7 | GHD | Weight loss | Headache, nausea/vomit | TQ RE |
| 4 | F | 15 | GHD, HG, HC | Somnolence | Headache, nausea/vomit | Papilloedema, optic atrophy LE, BH |
| 5 | F | 8 | No | Hyperphagia, OB, somnolence | Headache, hemiparesis, ptosis LE | AM |
| 6 | M | 9 | GHD, HC, hyperprolactinemia | Somnolence | Headache, nausea/vomit | AM LE/TH RE |
| 7 | F | 10 | DI | OB | Headache | Papilloedema, TH LE |
| 8 | M | 14 | No | OB | Headache | BH |
| 9 | M | 16 | GHD, DI, HT, HG, HC | – | – | |
| 10 | M | 20 | No | OB | – | BH |
| 11 | F | 21 | DI, HT, HG, HC, hyperprolactinemia | – | Headache, nausea/vomit | BH |
| 12 | F | 22 | GHD, HT, HG, HC | OB | Headache | BH |
| 13 | M | 26 | GHD, DI, HT, HG, HC | OB | – | – |
| 14 | F | 27 | DI, HG, HC | Somnolence | Nausea/vomit | – |
| 15 | M | 30 | HT, HG, HC | Hyperphagia, OB, somnolence | Headache | Diplopia |
| 16 | F | 55 | No | Weight loss | – | TQ LE |
M male, F female, DI diabetes insipidus, GHD growth hormone deficiency, HT hypothyroidism, HG hypogonadism, HC hypocortisolism, OB obesity, LE left eye, RE right eye, BH bitemporal hemianopsia, AM amaurosis, TH temporal hemianopsia, TQ temporal quadranopsia