Fig. 5.
EIF3A is a novel estrogen-responsive gene that affects the growth and migration of MCF-7 cells. a Genome view shows RNA fragments mapped on EIF3A. b Quantification of mapped fragments onto EIF3A indicated the E2 responsiveness. c qRT-PCR confirmed the E2 responsiveness of EIF3A. d MTS assay indicated that the growth of MCF-7 cells was decreased by the knockdown of EIF3A. e Trans-well assay indicated that the migration of MCF-7 cells was decreased by the knockdown of EIF3A. Student’s t test was performed between each siRNA sample and siControl sample (**P < 0.01)