Table 2.

Results of mitotane monochemotherapy

Author, year; study type (n)	Dosage, g/day	Standardized CT	WHO criteria	Tumor response, n (%)	Duration, months
Venkatesh, 1989; retrospective (72)	NA	No	No	21 (29)	NA
Luton, 1990; retrospective (37)	3–20	No	No	5 (13)	5–25
Decker, 1991; prospective (36)	6	No	Yes	8 (22)	3–82
Pommier, 1992; retrospective (29)	NA	No	No	7 (24)	NA
Haak, 1994; retrospective (55)	4–8	No	Yes	15 (27)	2–190
Barzon, 1997; retrospective (11)	4–8	Yes	Yes	2 (18)	12–21
Williamson, 1999; prospective (16)	4–10	No	Yes	2 (13)	NA
Baudin, 2001; prospective (13)	6–12	Yes	Yes	4 (33)	10–48

NA not available