Fig. 1.

Effect of increasing doses of Tamoxifen on uterine weights (a), body weights (b), and liver weights and enzymes (c) in wild-type mice. Groups of 3-week-old wild-type mice (n = 10/group) were placed on a 20% CO diet containing the indicated doses of Tamoxifen or no drug until they were sacrificed at week 14 of age (see “Materials and Methods” section for details). Data are expressed as means ± SE