Table 1.

Neuroblastoma cell clones

Clone	Variation	Type of mutation
pcDNA	Empty vector	No
SDHB	Wild type	No
SDHB	c.302 G > A p.Cys101Tyr	Missense
SDHB	c.572 G > A p.Cys191Tyr	Missense
SDHB	c.487 T > C p.Ser163Pro	Missense

cDNA for wild-type SDHB subunit was cloned, and cDNAs corresponding to mutations were generated by site-directed mutagenesis on the wild-type sequence. Neuroblastoma cells were stably transfected with the different constructs. pcDNA and SDHB wt clones were used as controls