FIGURE 3.

BCLET transcripts significantly inhibited tumor proliferation in vitro and in vivo. The effect of BCLET transcripts overexpression on cell viability was detected by CCK‐8 (A) and colony formation assays (B) in T24 cell lines. Tumor burdens after inoculation with LV‐BCLET‐long/LV‐BCLET‐short and LV‐NC were examined in nude mice (C) and their xenografts (D). (E) The tumor volumes were measured. (F) The tumor weights in the nude mice were determined after 4 weeks. (G) Representative images of HE and immunohistochemical staining for Ki67 and MSANTD2 in mouse tumors (scale bars = 50 μm).