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. 2023 May 15;12(13):14452–14467. doi: 10.1002/cam4.6074

FIGURE 5.

FIGURE 5

USP10 positively regulates YAP1 protein expression in osteosarcoma cells. (A, B) In response to the knockdown or upregulation of USP10 expression levels in OS cells, the protein expression levels of YAP1 also changed significantly, however, the change in its mRNA levels was not statistically significant (ns, not significant). (C, D) Detection of YAP1 protein and mRNA expression in OS and paired non‐tumor tissues via western blot and qRT‐PCR. (**p < 0.01; N, normal; t, tumor). (E) Representative images (left) and quantification (right) of YAP1 IHC staining in 51 paired OS tumor and their corresponding adjacent tissues (**p < 0.01). (F) The scatter plot depicted that the protein expression levels of YAP1 and USP10 in OS tissues were positively correlated.