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. 2023 May 15;12(13):14452–14467. doi: 10.1002/cam4.6074

FIGURE 6.

FIGURE 6

YAP1 is essential in USP10‐mediated EMT and migration of OS cells. (A) The P‐YAP1 plasmid was transfected into U2‐OS cells stably transfected with shUSP10, and the expression of YAP1 and EMT‐related proteins was shown by western blotting. (B) In U2‐OS cells, the decrease in invasion and migration induced by shUSP10 could be partially offset by P‐YAP1 as detected by transwell test (*p < 0.05, **p < 0.01). (C) The shYAP1 plasmid was transfected into MG‐63 cells stably transfected with P‐USP10, and the expression of YAP1 and EMT‐related proteins was shown by western blotting. (D) In MG‐63 cells, the enhancement of invasion and migration mediated by P‐USP10 was partially counteracted by shYAP1, as determined by transwell assays (*p < 0.05, **p < 0.01).