TABLE 3.

Results of the meta‐regression analysis of the included studies.

	Parameters	Regression coefficient	Lower limit	Upper limit	p‐value
ORR	Median age	0.00	−0.04	0.04	0.90
	Median OS	0.05	0.04	0.07	<0.001
	Year of publication	0.01	−0.00	0.02	0.14
	Previous systemic therapy	−0.00	−0.01	−0.00	<0.001
	Previous radiation therapy	−0.01	−0.02	−0.00	<0.001
DCR	Median age	0.01	−0.02	0.04	0.53
	Median OS	0.04	0.03	0.06	<0.001
	Year of publication	0.01	−0.00	0.02	0.052
	Previous systemic therapy	−0.00	−0.00	−0.002	<0.001
	Previous radiation therapy	−0.00	−0.01	−0.00	0.003

Abbreviations: DCR, disease control rate; ORR, overall response rate; OS, overall survival;