Table 3.
Risk factors for seven-day stroke in univariate analysis.
| Variables | No stroke N=654 (96.5%) |
Stroke N=24 (3.5%) |
RR | 95% CI | P-value |
|---|---|---|---|---|---|
| Age* | 61.4±10.8 | 62.5±97 | 1.0 | 0.975 - 1.045 | 0.607 |
| Female | 202 (30.9) | 7 (29.1) | 0.9 | 0.389 - 2.194 | 0.858 |
| SAH | 537 (82.1) | 19 (79.2) | 0.8 | 0.318 - 2.190 | 0.712 |
| DM | 228 (34.9) | 12 (50) | 1.8 | 0.833 - 3.999 | 0.133 |
| Obesity | 141 (21.6) | 6 (25) | 1.3 | 0.511 - 3.220 | 0.595 |
| Active smoking | 125 (19.1) | 3 (12.5) | 0.5 | 0.143 - 1.777 | 0.287 |
| COPD | 26 (4.0) | 2 (8.3) | 2.1 | 0.522 - 8.534 | 0.295 |
| Ischemic heart disease | 503 (76.9) | 19 (79.1) | 1.1 | 0.431 - 2.992 | 0.797 |
| Recent heart attack (< 90 days) | 207 (31.6) | 7 (29.2) | 0.9 | 0.394 - 2.257 | 0.894 |
| Ejection fraction ≤ 40% | 69 (10.5) | 3 (12.5) | 1.1 | 0.349 - 3.730 | 0.827 |
| Ejection fraction* | 58.3±12.1 | 57.6±12.4 | 1.0 | 0.965 - 1.027 | 0.780 |
| Carotid disease | 201 (30.7) | 15 (62.5) | 4.3 | 1.594 - 11.708 | 0.004 |
| Previous TIA/stroke | 55 (8.4) | 6 (25) | 3.3 | 1.377 - 8.095 | 0.008 |
| PAD | 39 (6.0) | 3 (12.5) | 2.2 | 0.672 - 6.961 | 0.196 |
| Creatinine clearance* | 71.2±26.7 | 67.3±18.5 | 1.0 | 0.983 - 1.006 | 0.340 |
| Endocarditis | 23 (3.5) | 2 (8.3) | 2.4 | 0.591 - 9.546 | 0.223 |
| Previous atrial fibrillation | 56 (8.6) | 5 (20.8) | 2.6 | 1.027 - 6.856 | 0.044 |
| Decompensated CHF | 301 (46.0) | 12 (50.0) | 1.2 | 0.529 - 2.545 | 0.712 |
| Preoperative hemoglobin | 13.0±1.8 | 12.6±1.8 | 0.9 | 0.732 - 1.085 | 0.250 |
| Preoperative platelets (×103/mm3)* | 224.3±69.6 | 266.4±100.3 | 1.1 | 1.021 - 1.105 | 0.003 |
| Preoperative INR | 1.1 (1.0; 1.1) | 1.1 (1.1; 1.2) | 3.7 | 0.958 - 14.403 | 0.058 |
| Previous cardiac surgery | 27 (4.1) | 2 (8.3) | 2.0 | 0,502 - 8.241 | 0.320 |
| Emergency surgery | 347 (53.1) | 14 (58.3) | 1.2 | 0,552 - 2.720 | 0.617 |
| Procedure type | |||||
| MRS | 445 (68.0) | 16 (66.7) | 1.0 | - | - |
| Valve exchange | 132 (20.2) | 2 (8.3) | 0.4 | 0.100 - 1.847 | 0.114 |
| Combined procedure | 77 (11.8) | 6 (25) | 2.1 | 0.839 - 5.168 | 0.256 |
| ECC time ≥ 110 min | 215 (32.9) | 9 (37.5) | 1.3 | 0.553 - 2.859 | 0.585 |
| CPB time* | 102.7±35.3 | 108.8±38.7 | 1.0 | 0.995 - 1.014 | 0.393 |
| Cardiogenic shock | 107 (16.3) | 6 (25) | 1.7 | 0.677 - 4.106 | 0.267 |
| CRP/ventricular arrhythmias | 68 (10.4) | 4 (16.7) | 1.7 | 0.592 - 4.788 | 0.329 |
| Acute atrial fibrillation | 207 (31.6) | 8 (33.3) | 1.1 | 0.467 - 2.472 | 0.866 |
| Postoperative fibrinogen* | 260.2±102.3 | 264.6±101.5 | 1.0 | 0.997 - 1.004 | 0.831 |
*
mean ± standard deviation
CHF=congestive heart failure; CI=confidence interval; COPD=chronic obstructive pulmonary disease; CPB=cardiopulmonary bypass; CRP=cardiorespiratory arrest; DM=diabetes mellitus; ECC=extracorporeal circulation; INR=international normalized ratio; MRS=myocardial revascularization surgery; PAD=peripheral arterial disease; RR=relative risk; SAH=systemic arterial hypertension; TIA=transient ischemic attack