Table 2. 2-Sulfonyl/Sulfonamide Pyrimidine Potency with Low and High ATP Concentrations.
| compound | 60 μM ATP; IC50 (nM) | 1 mM ATP; IC50 (nM) |
|---|---|---|
| H3B-859 | 775 | >50,000 |
| H3B-219 | 881 | >50,000 |
| H3B-960 | 225 | 894 |
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