Table 3. 2-Sulfonyl/Sulfonamide Pyrimidine Potency with Low and High DNA Concentrations.
| compound | 50 nM DNA; IC50 (nM) | 500 nM DNA; IC50 (nM) |
|---|---|---|
| H3B-859 | 534 | 235 |
| H3B-219 | 313 | 385 |
| H3B-960 | 57 | 36 |
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