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Biobehavioral model for stressors, psychological responses, neuroendocrine activity, and impact on peripheral tissue in cancer and their interactions with cognitive behavioral therapy (CBT)-based stress management interventions. Abbreviations: ACTH, adrenocorticotrophic hormone; HPA, hypothalamic-pituitary-adrenal; IL, interleukin; MMP, matrix metalloprotease; VEGF, vascular endothelial growth factor.
