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. 2023 Apr 10;18(12):2773–2780. doi: 10.4103/1673-5374.373660

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SynGO enrichment analysis of genes upregulated in ZnT3 conditional knockout RGCs.

(A) Sunburst plots of SynGO-enrichment analyses of locations (cellular components) for 560 CKO upregulated genes comparing the transcriptomes of ONC only group (CKO/ONC, fold change > 2, P < 0.05). (B) Sunburst plots of SynGO-enrichment analyses of functions (biological processes) for 560 CKO-upregulated genes when comparing the transcriptomes of ONC only group (CKO/ONC, fold change > 2, P < 0.05). Color code denotes the gene count, including child terms. CKO: Conditional knockout; ONC: optic nerve crush; RGC: retinal ganglion cell; SynGO: synapse Gene Ontology; ZnT3: zinc transporter 3.