Additional Table 2.
Gene Ontology of the up-regulated cluster related to Figure 7
| GO ID | Description | generatio | BgRatio | Pvalue | Gene_name |
|---|---|---|---|---|---|
| Cellular component | |||||
| GO:0005886 | Plasma membrane | 84 | 5576 | 0.018367 | Alcam, Art3, Abcb11, Slc51a, Pcdhb18, Vwc2, Cd247, Acvr1, Unc5c, Olfr1437, Arhgap45, Pcdhb5, Pcdhb16, Kctd16, Evc, Nkain4, Chrna5, Npc1l1, Rgs13, C8g, Vmn1r4, Ackr4, Tmprss9, Ace, Slc22a27, Btla, Tshr, Utrn, Cd79a, Gpr161, Csmd3, Gabrq, Clec5a, Pcdhb9, Plcb1, Frk, Tmem65, Gab2, Fmnl3, Clec2g, Amhr2, Pcdhb19, Kcnmb4, Pcsk9, Adcy10, Pcdhb11, Nkain3, Pcdha8, Fhit, Pcdhb8, Gng10, Astn1, Tgfbr3, Pcdh20, Pcdhgc3, Trpm4, Ptprk, Clstn2, Pcdhgb1, Neto2, Aoc3, 1700019D03Rik, Olfr1254, Ptprcap, Ocln, Pcdhb4, Tek, Vmn1r200, Slc7a3, Ptgdr2, Dsg2, Stbd1, Gpr158, Car15, H2-M3, Pik3cg, Hspb1, Lama2, Lat, Scn9a, Il1rapl1, Tyrobp, Pcdha11, Pcdhga5 |
| GO:0016020 | Membrane | 84 | 5576 | 0.018367 | Alcam, Art3, Abcb11, Slc51a, Pcdhb18, Vwc2, Cd247, Acvr1, Unc5c, Olfr1437, Arhgap45, Pcdhb5, Pcdhb16, Kctd16, Evc, Nkain4, Chrna5, Npc1l1, Rgs13, C8g, Vmn1r4, Ackr4, Tmprss9, Ace, Slc22a27, Btla, Tshr, Utrn, Cd79a, Gpr161, Csmd3, Gabrq, Clec5a, Pcdhb9, Plcb1, Frk, Tmem65, Gab2, Fmnl3, Clec2g, Amhr2, Pcdhb19, Kcnmb4, Pcsk9, Adcy10, Pcdhb11, Nkain3, Pcdha8, Fhit, Pcdhb8, Gng10, Astn1, Tgfbr3, Pcdh20, Pcdhgc3, Trpm4, Ptprk, Clstn2, Pcdhgb1, Neto2, Aoc3, 1700019D03Rik, Olfr1254, Ptprcap, Ocln, Pcdhb4, Tek, Vmn1r200, Slc7a3, Ptgdr2, Dsg2, Stbd1, Gpr158, Car15, H2-M3, Pik3cg, Hspb1, Lama2, Lat, Scn9a, Il1rapl1, Tyrobp, Pcdha11, Pcdhga5 |
| GO:0071944 | Cell periphery | 84 | 5578 | 0.01853 | Alcam, Art3, Abcb11, Slc51a, Pcdhb18, Vwc2, Cd247, Acvr1, Unc5c, Olfr1437, Arhgap45, Pcdhb5, Pcdhb16, Kctd16, Evc, Nkain4, Chrna5, Npc1l1, Rgs13, C8g, Vmn1r4, Ackr4, Tmprss9, Ace, Slc22a27, Btla, Tshr, Utrn, Cd79a, Gpr161, Csmd3, Gabrq, Clec5a, Pcdhb9, Plcb1, Frk, Tmem65, Gab2, Fmnl3, Clec2g, Amhr2, Pcdhb19, Kcnmb4, Pcsk9, Adcy10, Pcdhb11, Nkain3, Pcdha8, Fhit, Pcdhb8, Gng10, Astn1, Tgfbr3, Pcdh20, Pcdhgc3, Trpm4, Ptprk, Clstn2, Pcdhgb1, Neto2, Aoc3, 1700019D03Rik, Olfr1254, Ptprcap, Ocln, Pcdhb4, Tek, Vmn1r200, Slc7a3, Ptgdr2, Dsg2, Stbd1, Gpr158, Car15, H2-M3, Pik3cg, Hspb1, Lama2, Lat, Scn9a, Il1rapl1, Tyrobp, Pcdha11, Pcdhga5 |
| Molecular function | |||||
| GO:0043167 | Ion binding | 90 | 5936 | 0.025628 | Gm2004, Ttll9, Abcb11, Zfp429, Pcdhb18, Acvr1, Peg10, Snx33, Arhgap45, Pcdhb5, Fblim1, Pcdhb16, Lrp1b, Mos, 1110008L16Rik, Zfp975, Crip3, Chrna5, Zfp979, Nlrp4f, Zbtb7c, Epha6, Atp13a5, Ddx43, Osbpl10, Fstl4, Qpct, Adamts12, Zfp92, Ace, Gm38394, Nr1h4, Rasef, Gm10324, Utrn, Glis3, Pcdhb9, Bche, Gm32687, Plcb1, Col5a2, Frk, Fthl17f, Efhc1, Slc22a21, Plekhf1, Gm14322, Mapkapk3, Amhr2, Pla2g4a, Pcdhb19, Zfp931, Mex3c, Galnt18, Adcy10, Pcdhb11, Gm19410, Gstm7, Pcdha8, Fhit, Pcdhb8, Klf11, Tgfbr3, Pcdh20, Pcdhgc3, Trpm4, Hmgcll1, Plcz1, Hapln4, Rnf19b, Npr3, Clstn2, Stk32b, Pcdhgb1, Alpk1, Aoc3, Zfp850, Reps2, Pcdhb4, Tek, Dsg2, Gm6871, Car15, Pik3cg, Scn9a, Zfp595, Zfp119b, Papolb, Pcdha11, Pcdhga5 |
| GO:0032182 | Ubiquitin-like protein binding | 4 | 108 | 0.048709 | Rnf19b, Ddi1, Hspb1, Simc1 |
| Biological process | |||||
| GO:0007155 | Cell adhesion | 32 | 1234 | 8.88E-05 | Alcam, Pcdhb18, Vwc2, Acvr1, Pcdhb5, Fblim1, Pcdhb16, Adamts12, Utrn, Bmp5, Pcdhb9, Plcb1, Pcdhb19, Pcdhb11, Pcdha8, Pcdhb8, Astn1, Pcdh20, Pcdhgc3, Hapln4, Ptprk, Clstn2, Pcdhgb1, Aoc3, Pcdhb4, Tek, Dsg2, H2-M3, Lama2, Lat, Pcdha11, Pcdhga5 |
| GO:0022610 | Biologicaladhesion | 32 | 1234 | 8.88E-05 | Alcam, Pcdhb18, Vwc2, Acvr1, Pcdhb5, Fblim1, Pcdhb16, Adamts12, Utrn, Bmp5, Pcdhb9, Plcb1, Pcdhb19, Pcdhb11, Pcdha8, Pcdhb8, Astn1, Pcdh20, Pcdhgc3, Hapln4, Ptprk, Clstn2, Pcdhgb1, Aoc3, Pcdhb4, Tek, Dsg2, H2-M3, Lama2, Lat, Pcdha11, Pcdhga5 |
| GO:0032502 | Developmental process | 93 | 5644 | 0.001767 | Alcam, Csrnp1, Cnmd, Shcbp1l, Hnmt, Dmbx1, Vwc2, Syt17, Acvr1, Unc5c, Peg10, Sct, Armc4, Fblim1, Rai14, Pcdhb16, Evc, Id4, Bend6, Dnaic1, C1galt1c1, Zbtb7c, Evi2, Pnpt1, Ttc9, Fstl4, Adamts12, Ehf, Cdkn2b, Ace, Gm38394, Nr1h4, Tshr, Utrn, Cd79a, Gpr161, Csmd3, Bmp5, Clec5a, Bche, Plcb1, Col5a2, Frk, Tmem65, Mycl, Efhc1, Gab2, Fmnl3, Clec2g, Amhr2, Pla2g4a, Pcsk9, Mex3c, Pax5, Klf1, Mospd1, Otor, Dusp6, Astn1, Tgfbr3, Etl4, Trpm4, Plcz1, Sema3a, Npr3, Maf, Ptprk, Clstn2, Tbx6, Kbtbd8, Ptf1a, Neurog2, Dazl, Pgf, Arhgap15, Tek, Nat1, Dsg2, Klhl10, H2-M3, Hey1, Pik3cg, Dnajb9, Hspb1, Lama2, Hesx1, Scn9a, Tal2, Il1rapl1, Tyrobp, Trappc2, Tdrd5, Dact1 |
| GO:0048856 | Anatomical structure development | 88 | 5284 | 0.001824 | Alcam, Csrnp1, Cnmd, Hnmt, Dmbx1, Vwc2, Syt17, Acvr1, Unc5c, Peg10, Sct, Armc4, Fblim1, Pcdhb16, Evc, Id4, Bend6, Dnaic1, C1galt1c1, Evi2, Pnpt1, Ttc9, Fstl4, Adamts12, Ehf, Cdkn2b, Ace, Gm38394, Nr1h4, Tshr, Utrn, Cd79a, Gpr161, Csmd3, Bmp5, Clec5a, Bche, Plcb1, Col5a2, Tmem65, Mycl, Efhc1, Gab2, Fmnl3, Clec2g, Amhr2, Pla2g4a, Pcsk9, Mex3c, Pax5, Klf1, Otor, Dusp6, Astn1, Tgfbr3, Etl4, Trpm4, Plcz1, Sema3a, Npr3, Maf, Ptprk, Clstn2, Tbx6, Kbtbd8, Ptf1a, Neurog2, Dazl, Pgf, Arhgap15, Tek, Nat1, Dsg2, Klhl10, H2-M3, Hey1, Pik3cg, Dnajb9, Hspb1, Lama2, Hesx1, Scn9a, Tal2, Il1rapl1, Tyrobp, Trappc2, Tdrd5, Dact1 |
| GO:0048869 | Cellular developmental process | 62 | 3861 | 0.022863 | Alcam, Cnmd, Shcbp1l, Vwc2, Syt17, Acvr1, Unc5c, Peg10, Fblim1, Rai14, Id4, Bend6, C1galt1c1, Zbtb7c, Evi2, Fstl4, Adamts12, Ehf, Cdkn2b, Ace, Tshr, Cd79a, Csmd3, Bmp5, Clec5a, Bche, Plcb1, Col5a2, Frk, Mycl, Gab2, Fmnl3, Clec2g, Pcsk9, Mex3c, Pax5, Klf1, Mospd1, Dusp6, Astn1, Tgfbr3, Trpm4, Sema3a, Maf, Ptprk, Tbx6, Kbtbd8, Ptf1a, Neurog2, Dazl, Pgf, Arhgap15, Tek, Klhl10, H2-M3, Hey1, Dnajb9, Hspb1, Lama2, Tyrobp, Tdrd5, Dact1 |
| GO:0044767 | Single-organism developmental process | 69 | 4385 | 0.024452 | Alcam, Cnmd, Shcbp1l, Vwc2, Syt17, Acvr1, Unc5c, Peg10, Sct, Fblim1, Rai14, Id4, Bend6, C1galt1c1, Zbtb7c, Evi2, Pnpt1, Fstl4, Adamts12, Ehf, Cdkn2b, Ace, Gm38394, Tshr, Cd79a, Gpr161, Csmd3, Bmp5, Clec5a, Bche, Plcb1, Col5a2, Frk, Mycl, Gab2, Fmnl3, Clec2g, Pcsk9, Mex3c, Pax5, Klf1, Mospd1, Dusp6, Astn1, Tgfbr3, Etl4, Trpm4, Sema3a, Maf, Ptprk, Tbx6, Kbtbd8, Ptf1a, Neurog2, Dazl, Pgf, Arhgap15, Tek, Nat1, Klhl10, H2-M3, Hey1, Dnajb9, Hspb1, Lama2, Hesx1, Tyrobp, Tdrd5, Dact1 |
| GO:0030154 | Cell differentiation | 59 | 3757 | 0.039332 | Alcam, Cnmd, Shcbp1l, Vwc2, Syt17, Acvr1, Unc5c, Peg10, Rai14, Id4, Bend6, C1galt1c1, Zbtb7c, Evi2, Fstl4, Adamts12, Ehf, Cdkn2b, Ace, Tshr, Cd79a, Csmd3, Bmp5, Clec5a, Bche, Plcb1, Col5a2, Frk, Mycl, Gab2, Clec2g, Pcsk9, Mex3c, Pax5, Klf1, Mospd1, Dusp6, Astn1, Tgfbr3, Trpm4, Sema3a, Maf, Ptprk, Tbx6, Kbtbd8, Ptf1a, Neurog2, Dazl, Pgf, Tek, Klhl10, H2-M3, Hey1, Dnajb9, Hspb1, Lama2, Tyrobp, Tdrd5, Dact1 |