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. 2023 Jul 17;18(1):20220652. doi: 10.1515/biol-2022-0652

Table 3.

Associations between pathways and prognosis in ICCA patients

Pathway p-Value
PFS OS
p53 signaling pathway 0.683091 1
PD-L1 expression and PD-1 checkpoint pathway in cancer 0.214193 0.08201
T cell receptor signaling pathway 1 0.066393
Cell cycle 0.683091 1
Natural killer cell mediated cytotoxicity 1 0.066393
Platinum drug resistance 0.619297 0.771926
Insulin signaling pathway 0.567628 0.182287
mTOR signaling pathway 1 0.333949
JAK-STAT signaling pathway 0.396144 0.226256
EGFR tyrosine kinase inhibitor resistance 0.619297 0.333949
Wnt signaling pathway 0.683091 1
Proteoglycans in cancer 0.706082 0.825863
Rap1 signaling pathway 0.619297 0.333949
Ras signaling pathway 0.298698 0.544329
Signaling pathways regulating pluripotency of stem cells 0.298698 0.544329
MAPK signaling pathway 0.362355 0.333949
FoxO signaling pathway 0.665006 0.544329
Hepatocellular carcinoma 0.100348 1
PI3K-Akt signaling pathway 0.706082 0.825863
MicroRNAs in cancer 0.706082 0.825863