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. Author manuscript; available in PMC: 2023 Jul 20.
Published in final edited form as: Nat Comput Sci. 2022 Dec 29;3(1):71–85. doi: 10.1038/s43588-022-00390-2

Figure 1: Dimensionality reduction of calcium imaging recordings.

Figure 1:

A key property of calcium imaging is the slow decay of the measured fluorescence (left panel, maroon) after each spiking event (left panel, grey). If ignored, the calcium decay could introduce temporal correlations in the estimated latent variables (right panel, maroon), where those temporal correlations would not be present had we estimated the latent variables from the underlying spike trains (right panel, grey).