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. 2023 Jul 6;14:1170035. doi: 10.3389/fimmu.2023.1170035

Table 2.

Major eosinophil receptors.

Cytokine receptors Pattern-recognition receptors (PRRs) Chemokine receptors
IL-2R TLR1 CCR3
IL-3R (CD123) TLR5 CCR1
IL-4R TLR7 CCR2
IL-5R (CD125) TLR8 CXCR3
IL-9R TLR9 CXCR4
IL-10R TLR2 CCR4
IL-13R TLR3 CCR5
IL-17R TLR4 CCR6
IL-23R TLR6 CCR8
IL-27R TLR10 CCR9
IL-31R NOD1 CXCR2
IL-33R NOD2 FPR1
TSLPR RIGs
GM-CSFR (CD116) RAGE Complement receptors
c-kit (CD117) CR1 (CD35)
IFN-γR Immunoglobulin receptors CR3bi (Mac1; CD11b–CD18)
TGF-βR FCaR (CD89) CD88 (C5aR)
CD131 FCgRII (CD32) C3aR
IL-1R FcϵRI*
TNF-αR FcϵRII Inhibitory receptors
FCgRIIB (CD32)
Adhesion molecules Lipid mediator receptors LIR3 (CD85a)
CD62L (L-selectin) DP2 prostaglandin receptor (CRTH2) KIR2DL3
CD162 (PSGL1) CysLT1R CD300a
CD15 (Sialil Lewis X) CysLT2R Siglec-8
CD34 PAFR Siglec-10
CD44 LTB4R
CD54 (ICAM-1) DP1 prostaglandin receptor Other receptors
CR3bi (Mac1; CD11b–CD18) EP2 prostaglandin receptor CD52
CR4 (CD11c–CD18) Histamine 4R
LFA-1 (CD11a–CD18) Proteinase-activated receptors CD95
VLA4 (CD49d–CD29) PAR1 CD69
2B4 (CD244) PAR2 Paired immunoglobulin-like receptor B (PIRB)
CD43 (lukosialin) MHCII
ESL-1 Costimulatory receptors PPAR γ
CD28
CD86

*Present on human eosinophils, but not in mouse eosinophils.