Table 3. Joinpoint trend analysis of age-standardized incidence and mortality rates due to pancreatic cancer worldwide, stratified by gender, during 1990–2019.
| Metric | Trend | Female | Male | Both | |||
|---|---|---|---|---|---|---|---|
| Year | APC (95%CI) | Year | APC (95%CI) | Year | APC (95%CI) | ||
| Incidence | |||||||
| Trend 1 | 1990–1994 | 1.30*(0.90, 1.60) | 1990–1994 | 1.20*(0.80, 1.50) | 1990–1994 | 1.20*(0.90, 1.60) | |
| Trend 2 | 1994–1997 | 0.30(-0.90, 1.50) | 1994–1997 | -0.40(-1.50, 0.80) | 1994–1997 | 0(-1.10, 1.10) | |
| Trend 3 | 1997–2008 | 1.0*(0.90, 1.10) | 1997–2010 | 1.20*(1.10, 1.30) | 1997–2009 | 1.10*(1.00, 1.20) | |
| Trend 4 | 2008–2019 | 0.5*(0.40, 0.60) | 2010–2019 | 0.40*(0.30, 0.50) | 2009–2019 | 0.40*(0.38, 0.50) | |
| AAPC | 1990–2019 | 0.80*(0.70, 0.90) | 1990–2019 | 0.80*(0.60, 0.90) | 1990–2019 | 0.80*(0.70, 0.90) | |
| Mortality | |||||||
| Trend 1 | 1990–1994 | 1.10*(0.80, 1.40) | 1990–1994 | 1.10*(0.70, 1.40) | 1990–1994 | 1.10*(0.80, 1.40) | |
| Trend 2 | 1994–1997 | 0.20(-0.60, 1.10) | 1994–1997 | -0.40(-1.50, 0.70) | 1994–1997 | -0.10(-1.00, 0.90) | |
| Trend 3 | 1997–2009 | 0.90*(0.89, 10) | 1997–2010 | 1.10*(1.07, 1.20) | 1997–2010 | 1.0*(0.98, 1.10) | |
| Trend 4 | 2009–2017 | 0.40*(0.30, 0.50) | 2010–2019 | 0.4*(0.30, 0.50) | 2010–2017 | 0.30*(0.20, 0.50) | |
| Trend 5 | 2017–2019 | 1.20*(0.30, 2.10) | 2017–2019 | 1.0*(0, 1.90) | |||
| AAPC | 1990–2019 | 0.80*(0.60, 0.90) | 1990–2019 | 0.70*(0.60, 0.80) | 1990–2019 | 0.80*(0.60, 0.90) | |
Note: APC Annual Percentage Change; AAPC Average Annual Percent Change; CI Confidence Interval. *Significantly different from 0 at alpha = 0.05 (p < 0.05). There are 1+(number of trend) joinpoints for each model.