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. 2023 Jun 27;24(4):bbad240. doi: 10.1093/bib/bbad240

Table 7.

The Wilcoxon signed-rank test for measuring the statistical significance of the performance between different approaches in terms of accuracy, F1, MCC and AUC

Accuracy
Wilcoxon P-value AMAP AMPDiscover-RF AMPDiscover-RNN AMPfun iAMP-CA2L iAMP-RAAC dbAMP
AMPDiscover-RF
AMPDiscover-RNN
AMPfun
iAMP-CA2L 0.008362
iAMP-RAAC 0.006714
dbAMP 0.030151 0.035339
iAMPCN 6.10E−05 6.10E−05 0.000122 6.10E−05 6.10E−05
F1
Wilcoxon P-value AMAP AMPDiscover-RF AMPDiscover-RNN AMPfun iAMP-CA2L iAMP-RAAC dbAMP
AMPDiscover-RF
AMPDiscover-RNN
AMPfun
iAMP-CA2L 0.187622
iAMP-RAAC 0.106995
dbAMP 0.002014 0.00061
iAMPCN 0.000122 6.10E−05 0.000122 0.000122 0.000305
MCC
Wilcoxon P-value AMAP AMPDiscover-RF AMPDiscover-RNN AMPfun iAMP-CA2L iAMP-RAAC dbAMP
AMPDiscover-RF
AMPDiscover-RNN
AMPfun
iAMP-CA2L 0.008362
iAMP-RAAC 0.008362
dbAMP 0.035339 0.047913
iAMPCN 6.10E−05 6.10E−05 6.10E−05 6.10E−05 0.000183 6.10E−05 6.10E−05
AUC
Wilcoxon P-value AMAP AMPDiscover-RF AMPDiscover-RNN AMPfun iAMP-CA2L iAMP-RAAC dbAMP
AMPDiscover-RF
AMPDiscover-RNN
AMPfun
iAMP-CA2L 0.008362
iAMP-RAAC 0.072998
dbAMP 0.035339 0.00116
iAMPCN 6.10E−05 6.10E−05 0.000122 6.10E−05 6.10E−05

‘–’ means that the number of functional activities that both tools can predict is less than 5.