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. 2023 Jul 4;12:e86454. doi: 10.7554/eLife.86454

Figure 7. MuMt- dihydrotestosterone (DHT)-induced mouse model phenotypic study.

Figure 7.

(a) Estrous cycles in muMt- control mice. (b) Estrous cycles in muMt- mice receiving DHT pellet implant. (c) Normalized anogenital distance 3 wk post pellet implantation. (d) Body weight (BW) at pellet implantation. (e) Weekly BW recordings. (f) EchoMRI record of fat and lean body composition. (g) Fasting glucose levels. (h) Oral glucose test results. (a–h) muMt- control mice (n = 12), muMt- mice receiving DHT pellet implant (n = 12). All bars indicate means, circles represent individual mice. In the case of missing values due to lack of measurement, mice were excluded from the analysis report for that variable. Unpaired Student’s t-test for analysis of anogenital distance difference between groups, as well as BW at implantation, fat mass, and fasting glucose; Mann–Whitney test for analysis of lean mass; two-way ANOVA with Sidak’s post hoc test for analysis of weekly BW recordings and blood glucose throughout the study; *p<0.05, **p<0.01, ***p<0.001.