Table 1. Clinical characteristics of women with polycystic ovary syndrome (PCOS) and women without the syndrome used for characterization of main B cell lineages and subpopulations based on pan B cell surface marker CD19.
| Controls(n = 22) | PCOS(n = 15) | p-Value | |
|---|---|---|---|
| Age (years) | 36.3 (21-50) | 26.4 (24-38) | 0.003 |
| Anthropometry | |||
| BMI (kg/m2) | 22.18 (18.31–32.15) | 24.39 (19.16–39.89) | 0.128 |
| Waist-to-hip-ratio | 0.8 (0.74–0.91) | 0.82 (0.71–0.92) | 0.237 |
| Endocrine measure | |||
| Free testosterone (ng/mL) | 0.25 (0,06–0.49) | 0.43 (0.02–0.88) | 0.037 |
| Total testosterone (ng/mL) | 0.86 (0.8–1.74) | 1.49 (0.07–3.05) | 0.037 |
| Free androgen index (FAI) | 1.2 (0.22–2.48) | 2.6 (0.11–20.34) | 0.003 |
| Androstenedione (ng/mL) | 2.8 (1.17–5.99) | 3.9 (2.27–6.53) | 0.003 |
| Metabolic measures | |||
| Cholesterol (mg/dL) | 177 (128–217) | 180 (135–214) | 0.469 |
| HDL (mg/dL) | 67 (46–87) | 51 (36–90) | 0.001 |
| LDL (mg/dL) | 97.3 (45.8–115.8) | 108.6 (78.6–160.4) | 0.049 |
| Triglycerides (mg/dL) | 65.5 (44-97) | 82 (56–124) | 0.011 |
| Glucose (mg/dL) | 88 (76–104) | 91 (77–111) | 0.491 |
Data are median ± range. Comparisons between groups were made using Mann–Whitney U-test.
BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein.