TABLE 3.
Univariate competing risk regression analysis of clinical factors and osteoradionecrosis
Induction chemotherapy | No induction chemotherapy | |||
---|---|---|---|---|
Variable | HR (95% CI) | P | HR (95% CI) | P |
Hypomagnesemia during treatment course | ||||
No | Reference | |||
Yes | 2.98 (1.15–7.68) | .024 | 0.94 (0.54–1.62) | .82 |
Radiation dose | 1.09 (0.97–1.22) | .15 | 0.99 (0.92–1.06) | .70 |
Dental extraction | ||||
No | Reference | |||
Yes | 1.20 (0.62–2.32) | .59 | 1.29 (0.85–1.95) | .24 |
Tumor (T classification) | ||||
Txa, T0 or T1 | ||||
T2 | 1.66 (0.35–7.84) | .52 | 1.65 (0.63–4.35) | .31 |
T3 | 1.55 (0.34–7.10) | .57 | 2.15 (0.79–5.85) | .13 |
T4 | 2.57 (0.60 10.95) | .20 | 2.74 (1.00–7.46) | .049 |
Alcohol use | ||||
No | Reference | |||
Yes | 1.34 (0.67–2.65) | .41 | 1.00 (0.58–1.71) | 1.00 |
Smoking | ||||
No | Reference | |||
Yes | 2.15 (1.03–4.48) | .041 | 1.14 (0.68–1.93) | .62 |
Note: The values marked in bold italics indicate statistical significance (P < .05).
Abbreviations: CI, confidence interval; HR, hazard ratio.
Tx refers no primary tumor.