TABLE IX.D.6.a.
Summary table for maxillary expansion for OSA
| Study | Year | LOE | Study design | Study group(s) | Clinical endpoints | Conclusions |
|---|---|---|---|---|---|---|
| Adults with OSA | ||||||
| Vinha et al.1855 | 2016 | 3a | Case series | 16 adults with maxillary transverse deficiency and OSA | AHI reduction of 56.2%; RDI reduction of 55%; ESS improvement; reduced desaturation and microarousals | SARME promotes an improvement in OSA symptoms, decreases the rates of respiratory disturbances, microarousal, and desaturation, and reduces daytime sleepiness. |
| Yoon et al.1857 | 2019 | 3a | Retrospective cohort study | 75 adult patients with OSA and narrow maxilla/nasal floor | Reduction of AHI from 17 to8 (53% change) | DOME treatment reduced the severity of OSA, refractory nasal obstruction, daytime somnolence, and increased the percentage of REM sleep. |
| Pediatric patients with OSA | ||||||
| Camacho et al.1851 | 2017 | 2a | Systematic review and meta-analysis | 314 children with transverse maxillary deficiency and OSA | AHI decrease of 70%; cure rate (AHI <1/h) for 90 patients was 26%; improved LSAT; more improvement in children after T&A or small tonsils | Improvement in AHI and lowest oxygen saturation has consistently been seen in children undergoing RME. |
| Machado et al.1853 | 2016 | 2a | Systematic review and meta-analysis | 215 children 0–12 year-old with OSA | Mean change in AHI after follow up was −6.9 | RME is an effective treatment for OSA. |
| Vale et al.1854 | 2017 | 2a | Systematic review and meta-analysis | Children younger than 18 years old with OSA that underwent RME | Statistically significant reduction in AHI after RME | RME reduced AHI in children with OSA, making RME therapy an appropriate alternative treatment option for these patients. |
| Cistulli et al.1852 | 1998 | 3a | Case study | 10 young adults with mild to moderate OSA and maxillary constriction | 90% of participants had improved snoring and hypersomnolence. Reduction in AHI from 19 to 7 | RME may be a useful treatment alternative for selected adults with OSA. |
| Quo et al.1860 | 2017 | 3a | Retrospective study | 45 children age 3–14 years with sleep disordered breathing | The majority of children showed improvement in sleep scores and symptoms after bimaxillary expansion | Bimaxillary expansion is a treatment option for improving respiratory parameters in children with sleep disordered breathing |