TABLE VI.A.1.
Evidence for the role of validated screening, functional outcomes, and health-related QOL questionnaires for OSA
| Study | Year | LOE | Study design | Study groups | Clinical endpoint | Conclusion |
|---|---|---|---|---|---|---|
| Nagappa423 | 2015 | 1a | Systematic review | 1. Sleep, 2. Surgical, 3. General | Meta-analysis of STOP-BANG | STOP-BANG is adequate screening tool in sleep and surgical patients. |
| Abrishami429 | 2010 | 1a | Systematic review | 1. Sleep, 2. Surgical, 3. General | Meta-analysis of OSA screening questionnaires | STOP-BANG and Berlin had similar sensitivities. Studies were heterogenous. |
| Amra430 | 2017 | 1a | Systematic review | 1. Sleep, 2. Surgical, 3. General | Comparison of OSA screening questionnaires. | STOP-BANG had best sensitivity and specificity for moderate OSA. |
| Chiu431 | 2016 | 1a | Systematic review | 1. Sleep, 2. Surgical, 3. General | Meta-analysis of STOP-BANG, Berlin, STOP, and ESS | STOP-BANG most accurate at detecting OSA at all severity cutoffs. |
| Senaratna422 | 2017 | 1a | Systematic review | 1. Sleep, 2. Surgical, 3. General | Meta-analysis of Berlin questionnaire | Berlin is adequate screening tool in sleep and surgical patients. Studies were heterogenous. |
| Billings437 | 2014 | 1b | Cohort | Sleep clinic | Comparing psychometric properties of SAQLI and FOSQ | Both demonstrate responsiveness to CPAP treatment. Comparable reliability and validity. |
| Coutinho424 | 2019 | 1b | Cohort | Sleep clinic | Validate NoSAS as screening tool for OSA | NoSAS is an adequate screening tool for OSA. |
| Marti-Soler426 | 2016 | 1b | Cohort | General | NoSAS derivation and validation. Comparison to other screening questionnaires. | NoSAS adequate screening tool compared with Berlin and STOP-BANG. |
| Silva441 | 2016 | 1b | Cohort | 1. OSA, 2. non-OSA | Comparison of SAQLI, FOSQ, SF-36 scores with OSA severity | Scores correlate w/OSA severity in females, but not males. All demonstrated convergent validity. |
| Abma444 | 2016 | 2a | Systematic review | 1. Sleep, 2. Non-sleep | Review of quality of PROMs for OSA | Most PROMs not adequately assessed due to low quality studies. |
| Mollayeva 443 | 2016 | 2a | Systematic review | 1. Sleep, 2. Non-sleep | Meta-analysis of psychometric properties of PSQI | Adequate reliability and validity as QOL tool. |
| Kendzerska436 | 2013 | 2a | Systematic review | 1. Sleep, 2. Non-sleep | Overview of psychometric properties of ESS | Convergent validity lower than expected. Few high quality studies. |
| Rong428 | 2019 | 2b | Cohort | 1. OSA, 2. Primary snorers | Comparison of NoSAS to STOP-BANG | NoSAS and STOP-BANG had comparable sensitivities and ROC. |
| Flemons439 | 2002 | 2b | Cohort | OSA | Evaluate psychometric properties of SAQLI | Adequate properties as a QOL instrument. |
| Flemons438 | 1998 | 2b | Cohort | 1. OSA, 2. Primary snorers | Derivation of SAQLI | Excellent internal consistency and responsiveness is present. |
| Hong425 | 2018 | 2b | Cohort | Sleep clinic | Comparison of NoSAS to STOP-BANG, ESS, and Berlin | NoSAS is an adequate screening tool for OSA. |
| Lacasse440 | 2002 | 2b | Cohort | Sleep clinic | Validation of SAQLI | Adequate validity and responsiveness to treatment. |
| Peng427 | 2018 | 2b | Cohort | 1. OSA, 2. Primary snorers | Comparison of screening questionnaires | NoSAS, Berlin, and STOP-BANG have comparable sensitivities. |
| Weaver442 | 1997 | 2b | Cohort | 1. Sleep, 2. Non-sleep | Derivation of FOSQ | FOSQ had excellent reliability and demonstrated known-groups validity. |
Abbreviations: ESS, Epworth Sleepiness Scale; FOSQ, functional outcomes sleep questionnaire; PROMs, patient reported outcomes measure; PSQI, Pittsburgh sleep quality index; SAQLI, sleep apnea quality of life index.