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. 2023 Jul 20;14:4369. doi: 10.1038/s41467-023-39982-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Core and accessory metabolic content was determined for 252 unique A. fumigatus strains of environmental and clinical origin. a Number of core and accessory genes, reactions (rxns), and metabolites for reconstructed strain-specific GEMs. b Summary of the core and accessory reactome for higher-level metabolic pathway categories. Pathway categories are according to KEGG pathway definition (https://www.kegg.jp/kegg/pathway.html). c Distribution of the accessory reactome across strain models. Indicated percentage ranges correspond to accessory reaction presence across strain-specific GEMs. Genetic relationship as originally published is indicated⁷. Source data for Fig. 2 are provided in the Source Data file.