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. 2023 May 3;109(15):1175–1182. doi: 10.1136/heartjnl-2022-322271

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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TEMPEST trial design. §May be performed at visit 1 or visit 2 but must be done before randomisation. AE, adverse event; BP, blood pressure; CMR, cardiovascular magnetic resonance; IMP, investigational medicinal product; ³¹P MRS, phosphorus-31 magnetic resonance spectroscopy; TEMPEST, The Efficacy and Mechanism of Trientine in Patients with Hypertrophic Cardiomyopathy.