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. 2023 May 29;51(13):6578–6592. doi: 10.1093/nar/gkad450

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Three methods were included in the comparison including scTenifoldKnk and two baseline predictors, which are based on random rankings and Pearson's correlation, respectively (Materials and Methods). (A) The procedure of assessment of virtual KO tools using simulated data sets. (B) The levels of AUROC of virtual KO experiments using three simulated SERGIO data sets. (C) The levels of AP of virtual KO experiments using three simulated SERGIO data sets. Size represents the number of genes in each data set.