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. 2023 Jul 6;13:1214977. doi: 10.3389/fonc.2023.1214977

Table 2.

Morphological and enhancement features of ICC and HCC.

HCC (n = 74) ICC (n = 39) p value*
Shape <0.0001†
 Round
 Lobulated
 Irregular
62 (83.8%)
7 (9.5%)
5 (6.8%)
14 (35.9%)
15 (38.5%)
10 (25.6%)
Demarcation <0.0001†
 Indistinct
 Well-defined area <50% of tumor margin Well-defined area >50% of tumor margin Sharp
4 (5.4%)
7 (9.5%)

5 (6.8%)

58 (78.4%)
9 (23.1%)
11 (28.2%)

8 (20.5%)

11 (28.2%)
Arterial enhancement pattern <0.0001†
 Homogeneous
 Heterogeneous
 Peripheral rim
 Not enhanced
33 (44.6%)
37 (50.0%)
4 (5.4%)
0 (0%)
7 (18.0%)
7 (18.0%)
21 (53.8%)
4 (10.3%)
Washout 73 (98.6%) 8 (20.5%) <0.0001†
Bile duct dilatation 5 (6.8%) 16 (41.0%) <0.0001†
Tortuous tumoral vessels 14 (18.9%) 3 (7.7%) 0.1664
fECV, mean ± SD, % 31.6 ± 9.0 43.8 ± 13.2 <0.0001†

fECV, extracellular volume fraction.

*Chi-square test or Fisher’s exact test or Welch’s t-test.

†Statistically significant.