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. 2023 Jun 22;26(7):107192. doi: 10.1016/j.isci.2023.107192

Figure 5.

Figure 5

IgG subclasses show a mixed profile after immunization with Pfs230D1-EPA/AS01 (0.3 μg) in CD-1 mice

Sera from CD-1 mice immunized with Research and Reference Lots of Pfs230D1-EPA/AS01 were collected on (A) Day 42 (2 weeks post-dose 2) and on (B) Day 155 (18 weeks post-dose 2), and pooled to determine IgG subclasses. Research Lot refers to the vaccine formulation used in these preclinical studies, while the Reference Lot more closely resembles the cGMP-manufactured material for human use. Data are presented as means with error bars indicating standard error of the mean of two technical replicates.