Extended Data Fig 6∣. ATAC Sequencing Tracks of TCL1A.
A. ATAC-sequencing tracks illustrating chromatin accessibility at rs2887399 in TET2 or DNMT3A-edited HSC/MPPs cultured for 5 days from donors of the GG, GT, and TT genotypes. Red line indicates location of rs2887399. TET2 edited samples are the same as in Figure 4, shown here for comparison. B. ATAC-sequencing tracks illustrating chromatin accessibility at rs2887399 in AAVS, TET2 or DNMT3A-edited HSC/MPPs cultured for 7 days from donors of the GG and TT genotypes, and then sorted for CD34hi CD38− CD45RA− Lin− cells prior to nuclei preparation. Red line indicates location of rs2887399.