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. 2023 Jul 3;145(28):15171–15179. doi: 10.1021/jacs.3c01902

Figure 5.

Figure 5

(A) Schematic illustration of eGFP to BFP conversion by co-delivery of Cas9 RNP and an ssDNA template into eGFP expressing cells. (B) Heat maps of NHEJ, HDR, total edited, and nonedited percentages in HeLa GFPd2 cells 48 h after treatment with Cas9 RNP/ssDNA nanocarriers (TFE-IDAtp1-LinA) at varied RNP concentrations and RNP/ssDNA ratios. (C) Heat map of HDR percentages in HeLa GFPd2 cells 48 h after treatment with different lipopeptide-based Cas9 RNP/ssDNA (fixed at 1/4) nanocarriers at varied RNP concentrations.