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. 2023 Jun 24;34(7):1271–1281. doi: 10.1021/acs.bioconjchem.3c00163

Figure 8.

Figure 8

Comparison of global scores, reactivity with Cys (k2 in s–1 M–1), and the conversion of oligopeptides (UP1, CGKGCGSGYGW; UP2, AGKGCGSGYGW). (A) Benchmark 6-amino-CBT and 6-hydroxy-CBT. (B) An overview of more reactive or more selective analogs with hydroxyl, amino, and carboxyl substituents that are readily available for functionalization.