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. 2023 Mar 15;18(11):2489–2496. doi: 10.4103/1673-5374.371399
The amount, distribution and context of methylated cytosine through the whole genome after spinal cord injury
Total C’s analysed mC in CpG mC in CHG mC in CHH mC in CH total mC UmCin CpG total CpG UmCin CHG total CHG UmCin CHH total CHH UmCin CH Total CH
shamJL 842,429,538 54,994,269 2,315,844 5,327,073 7,642,917 62,637,186 62,114,492 117,108,761 212,906,623 215,222,467 504,771,237 510,098,310 932,900,327 940,543,244
sham_2 685,890,086 44,962,151 1,759,987 4,022,632 5,782,619 50,744,770 53,746,413 98,708,564 173,979,806 175,739,793 407,419,097 411,441,729 757,138,696 762,921,315
sham_3 669,216,659 43,981,658 1,750,129 3,991,321 5,741,450 49,723,108 52,503,230 96,484,888 170,074,956 171,825,085 396,915,365 400,906,686 738,815,406 744,556,856
D0_1 740,058,636 47,277,785 1,938,121 4,514,325 6,452,446 53,730,231 53,951,243 101,229,028 185,587,957 187,526,078 446,789,205 451,303,530 819,903,240 826,355,686
D0_2 802,397,693 52,113,439 1,933,781 4,185,911 6,119,692 58,233,131 61,963,626 114,077,065 202,970,595 204,904,376 479,230,341 483,416,252 887,105,312 893,225,004
D0_3 835,534,708 54,163,266 1,998,758 5,012,725 7,011,483 61,174,749 55,864,246 110,027,512 203,860,943 205,859,701 514,634,770 519,647,495 924,355,414 931,366,897
Dl_l 563,865,388 35,026,270 1,226,164 2,950,892 4,177,056 39,203,326 39,677,439 74,703,709 138,783,034 140,009,198 346,201,589 349,152,481 624,993,821 629,170,877
Dl_2 794,989,317 51,221,832 1,872,044 4,300,220 6,172,264 57,394,096 63,158,771 114,380,603 200,480,716 202,352,760 473,955,734 478,255,954 876,789,210 882,961,474
Dl_3 601,484,603 38,846,925 1,223,920 2,694,908 3,918,828 42,765,753 41,142,248 79,989,173 149,698,141 150,922,061 367,878,461 370,573,369 668,498,663 672,417,491
D3_1 640,373,041 38,862,774 1,449,369 3,524,905 4,974,274 43,837,048 44,855,608 83,718,382 155,881,890 157,331,259 395,798,495 399,323,400 709,011,644 713,985,918
D3_2 734,842,848 45,495,979 1,781,328 4,453,384 6,234,712 51,730,691 52,298,130 97,794,109 180,014,308 181,795,636 450,799,719 455,253,103 812,609,663 818,844,375
D3_3 648,080,110 39,056,626 1,571,599 3,943,381 5,514,980 44,571,606 42,946,654 82,003,280 155,793,028 157,364,627 404,768,822 408,712,203 717,926,477 723,441,457
D7_1 724,092,220 44,860,645 1,628,173 3,412,579 5,040,752 49,901,397 53,097,892 97,958,537 182,199,685 183,827,858 438,893,246 442,305,825 804,920,789 809,961,541
D7_2 801,026,750 50,036,177 1,922,069 4,415,089 6,337,158 56,373,335 58,618,021 108,654,198 201,139,911 203,061,980 484,895,483 489,310,572 889,097,374 895,434,532
D7_3 887,027,971 55,145,861 1,759,801 3,811,845 5,571,646 60,717,507 65,068,186 120,214,047 223,856,907 225,616,708 537,385,371 541,197,216 986,858,986 992,430,632
D14_1 773,197,615 48,273,723 1,699,005 3,692,856 5,391,861 53,665,584 56,125,486 104,399,209 194,099,024 195,798,029 469,307,521 473,000,377 859,204,574 864,596,435
D14_2 751,529,174 45,467,695 1,428,734 3,140,148 4,568,882 50,036,577 54,811,715 100,279,410 187,318,211 188,746,945 459,362,671 462,502,819 835,427,827 839,996,709
D14_3 747,812,397 46,854,334 1,351,166 2,781,215 4,132,381 50,986,715 53,083,298 99,937,632 187,142,974 188,494,140 456,599,410 459,380,625 832,236,524 836,368,905
D28_1 865,031,656 53,965,853 2,050,638 4,973,766 7,024,404 60,990,257 62,481,622 116,447,475 216,014,310 218,064,948 525,545,467 530,519,233 959,624,725 966,649,129
D28_2 488,369,842 34,534,302 1,086,728 2,383,188 3,469,916 38,004,218 38,804,015 73,338,317 129,367,352 130,454,080 282,194,257 284,577,445 542,015,689 545,485,605
D28_3 711,340,972 44,133,614 1,631,822 3,757,447 5,389,269 49,522,883 53,942,098 98,075,712 178,506,315 180,138,137 429,369,676 433,127,123 788,014,128 793,403,397
D42_1 671,358,301 43,970,734 1,675,276 3,756,497 5,431,773 49,402,507 52,439,086 96,409,820 171,676,005 173,351,281 397,840,703 401,597,200 742,867,989 748,299,762
D42_2 730,293,196 47,608,062 1,786,388 3,945,949 5,732,337 53,340,399 54,943,465 102,551,527 185,879,442 187,665,830 436,129,890 440,075,839 809,675,162 815,407,499
D42_3 808,504,576 51,206,979 1,872,886 4,157,761 6,030,647 57,237,626 60,272,331 111,479,310 203,208,145 205,081,031 487,786,474 491,944,235 896,075,650 902,106,297
Max 887,027,971 55,145,861 2,315,844 5,327,073 7,642,917 62,637,186 65,068,186 120,214,047 223,856,907 225,616,708 537,385,371 541,197,216 986,858,986 992,430,632
Sham 2,197,536,283 143,938,078 5,825,960 13,341,026 19,166,986 163,105,064 168,364,135 556,961,385 1,309,105,699 1,866,067,084 1,885,234,070
DO 2,377,991,037 153,554,490 5,870,660 13,712,961 19,583,621 173,138,111 171,779,115 592,419,495 1,440,654,316 2,033,073,811 2,052,657,432
D1 1,960,339,308 125,095,027 4,322,128 9,946,020 14,268,148 139,363,175 143,978,458 488,961,891 1,188,035,784 1,676,997,675 1,691,265,823
D3 1,976,700,492 123,205,678 4,454,617 10,673,197 15,127,814 138,333,492 138,295,986 485,594,339 1,214,476,675 1,700,071,014 1,715,198,828
D7 2,412,146,941 150,042,683 5,310,043 11,639,513 16,949,556 166,992,239 176,784,099 607,196,503 1,461,174,100 2,068,370,603 2,085,320,159
D14 2,272,539,186 140,595,752 4,478,905 9,614,219 14,093,124 154,688,876 164,020,499 568,560,209 1,385,269,602 1,953,829,811 1,967,922,935
D28 2,064,742,470 132,633,769 4,769,188 11,114,401 15,883,589 148,517,358 155,227,735 523,887,977 1,237,109,400 1,760,997,377 1,776,880,966
D42 2,210,156,073 142,785,775 5,334,550 11,860,207 17,194,757 159,980,532 167,654,882 560,763,592 1,321,757,067 1,882,520,659 1,899,715,416