Table 1.
Comparisons of different brain regions between Con+eGFP and CSD+eGFP/CSD+Sirt6 and CSD+eGFP using functional magnetic resonance imaging
| Brain regions | Sirt6>Csd | Csd>Sirt6 | Con>Csd | Csd>Con | ||||
|---|---|---|---|---|---|---|---|---|
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| Voxel size | t-value | Voxel size | t-value | Voxel size | t-value | Voxel size | t-value | |
| Accumbens nucleus | 188 | 3.349 | 2245 | 5.342 | ||||
| Amygdala | 102 | 3.411 | 63 | 2.091 | 76 | 2.388 | 164 | 2.332 |
| Anterior olfactory nucleus | 642 | 4.617 | 306 | 4.429 | 361 | 2.949 | ||
| Caudate putamen | 143 | 2.833 | 696 | 4.357 | ||||
| Cerebellum | 2107 | 5.358 | 534 | 3.11 | 132 | 2.948 | ||
| Cingulate cortex | 14 | 1.943 | 62 | 3.142 | ||||
| Dentate gyrus | 57 | 2.262 | ||||||
| Ectorhinal cortex | 10 | 2.46 | ||||||
| Entorhinal cortex | 693 | 4.598 | ||||||
| Hippocampus | 21 | 2.238 | 27 | 2.124 | ||||
| Hypothalamus | 308 | 3.083 | ||||||
| Insular cortex | 501 | 3.067 | 628 | 3.611 | 46 | 2.342 | ||
| Primary motor cortex | 45 | 2.6 | 287 | 3.295 | ||||
| Secondary motor cortex | 47 | 2.854 | 286 | 3.108 | ||||
| Motor cortex | 318 | 3.356 | 1551 | 3.611 | ||||
| Olfactory bulb | 668 | 4.828 | 41 | 2.429 | 312 | 2.917 | ||
| Olfactory tubercle | 67 | 4.076 | 750 | 5.115 | ||||
| Orbital cortex | 980 | 3.291 | 43 | 3.401 | ||||
| Piriform cortex | 1348 | 5.115 | 7 | 1.923 | 2070 | 5.512 | 179 | 2.535 |
| Prelimbic cortex | 221 | 2.383 | 187 | 3.544 | ||||
| Preoptic nucleus | 17 | 2.813 | ||||||
| Retrosplenial granular cortex | 160 | 4.441 | ||||||
| Septal | 8 | 1.939 | 361 | 3.563 | ||||
| Somatosensory cortex | 45 | 2.387 | 727 | 3.823 | 159 | 3.436 | ||
| Subiculum | 85 | 3.021 | ||||||
| Tdalamus | 22 | 2.486 | ||||||
| Visual cortex | 264 | 3.819 | 47 | 2.912 | ||||
Con: Con + eGFP group; Csd: CSD + eGFP group; Sirt6: CSD + Sirt6 group. CSD: Chronic sleep deprivation; eGFP: enhanced green fluorescent protein; Sirt6: Sirtuins 6.