Figure 3.

Effects of RF-EMFs on the levels of Aβ and APP processing in the hippocampi of mice.

(A) Representative immunofluorescence images and quantification of Aβ (6E10 in red) in the hippocampi of 5×FAD mice after RF-EMFs exposure. (B and C) Representative images of Western blotting and the expression levels of APP, C99, Aβ, beta-secretase 1 (BACE1), and alpha-secretase (ADAM10) in the hippocampi of mice in the WT, TG-C, and TG-RF groups. The values are shown as the mean ± standard error of the mean. *P < 0.05, **P < 0.01 (n = 4 for A, n = 6 for C). Aβ: Amyloid-beta; APP: amyloid precursor protein; ns: not significant; TG-C: sham-exposed TG; TG-RF: radiofrequency electromagnetic fields-exposed TG; WT: wild-type.